Collaboration Details

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Title of Collaborative Activity:

HHS H5N1 Gain-of-Function Review Group (HHG Review Group)

Description of Collaborative Activity:

The Framework for Guiding HHS Funding Decisions about Research Proposals with the Potential for Generating Highly Pathogenic Avian Influenza (HPAI) H5N1 Viruses that are Transmissible among Mammals by Respiratory Droplets requires that certain research proposals undergo additional review at both the funding agency and Departmental (HHS) levels prior to funding. The HHS Department-level review is performed by the HHG Review Group, which brings to bear multidisciplinary interagency expertise in science, countermeasure development and availability, national security, law, public health preparedness and response, biodefense, select agent regulations, and science and public health policy. The purpose of the HHS Department-level review includes review of the funding agency's risk assessment, consideration of whether additional factors may alter assessment of whether the research can be funded, determination of which measures are needed to mitigate risks, consideration of the overall HHS influenza research portfolio, and determination of whether the proposal is acceptable for HHS funding.

Type of Collaborative Activity:

Committee, Advisory Group, or Work Group

Year the Collaborative Activity Originated:

2013

NIH Participating Institutes/Centers/Office of the Director:

NIAID, OD/OSP

HHS Agency Collaborators on this Activity:

CDC, FDA, OS