Description of Collaborative Activity: |
The overall goal in this project is to better characterize the hazards associated with personal exposure to common fungal contaminants in indoor and occupational environments. These studies will advance the understanding of the toxicological and pulmonary immune responses associated with subchronic natural fungal exposures. The data derived from these toxicology studies will further our understanding of the relevant species that are capable of eliciting adverse health effects. To address these aims, NIOSH will utilize an innovative acoustical generation system and state-of-the-art methodologies to characterize toxicological endpoints following subchronic dry fungal spore and particle exposures. In addition, these studies will characterize the pulmonary immune responses to fungal contaminants nominated by the NTP. |
