Description of Collaborative Activity: |
The NIH Gabriella Miller Kids First Common Fund Working Group supports the goals and initiatives of the NIH Gabriella Miller First Common Fund Pediatric Research Program.
In fiscal year 2015, in accordance with the Gabriella Miller Kids First Research Act, Congress appropriated $12.6 million to the NIH Common Fund to support pediatric research. The Common Fund’s Gabriella Miller Kids First Pediatric Research program (Kids First) is planning to develop a data resource for the pediatric research community of well-curated clinical and genetic sequence data that will allow scientists to identify genetic pathways that underlie specific pediatric conditions but that may also be shared between apparently disparate conditions. In order to make a significant impact within the available fiscal year 2015 budget, the program will collect data from the following types of pediatric conditions:
•Childhood cancers – Either those that have a suspected genetic component, or, as a jump start for the Precision Medicine Initiative which NIH expects to launch in fiscal year 2016, the program will also collect data from childhood sarcomas that have failed to respond to treatment.
•Structural birth defects - related to a problem with body parts and structure and include conditions like cleft lip, misshaped heart valves, abnormal limbs, problems related to the growth and development of the brain and spinal cord.
The integrated data resource will allow researchers to explore whether shared genetic pathways may contribute to both cancer and structural birth defects. |
Type of Collaborative Activity: |
Committee, Advisory Group, or Work Group
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NIH Participating Institutes/Centers/Office of the Director: |
NCI, NEI, NHGRI, NHLBI, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCR, NIDDK, NIEHS, NINDS, OD/DPCPSI/ORIP, OD/DPCPSI/OSC |
