Description of Collaborative Activity: |
The purpose of the Conducting Comprehensive Toxicological Assessments Agreement is to conduct comprehensive toxicological assessments on FDA priority chemicals/agents nominated to the National Toxicology Program at the FDA's National Center for Toxicological Research. Studies can include range finding sub-chronic and chronic, compound-specific mechanistic studies, and consideration of the use of alternate test systems. This combination of studies is designed to facilitate the interpretation of study results in support of comprehensive quantitative human health risk assessments. The primary goal of this program is to develop a comprehensive scientific database that can be utilized to reduce the uncertainty in risk assessment/risk-benefit analysis for specific chemicals with high FDA impact. |
