Collaboration Details

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Title of Collaborative Activity:

National COVID Cohort Collaborative (N3C)

Description of Collaborative Activity:

The N3C is a partnership among the NCATS-supported Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H), and NIGMS-supported Institutional Development Award Networks for Clinical and Translational Research (IDeA-CTR), to provide clinical data in close to real time to improve our knowledge of COVID-19 and potential treatment strategies. Collaborators will contribute and use COVID-19 clinical data to answer critical research questions to address the pandemic. As the largest limited dataset in US history with more than 11 Million participants (https://covid.cd2h.org/), the N3C initiative has demonstrated that it is possible to conduct science/learning healthcare across a large network, share and harmonize sensitive clinical data across modalities at a national scale and to realize the promise of precision medicine.The N3C effort is centered on the following:Establishing a secure data repository (the N3C Data Enclave) for studying COVID-19-related data.Receiving existing patient data derived from electronic health records (EHRs) provided by participating U.S. health care sites.Providing operational support for researchers using the N3C Data Enclave to navigate in the N3C platform and collaborate on COVID-19 research.Ensuring research using the N3C Data Enclave follows the rules and expectations of NCATS and its partners to keep the data secure and protect patient privacy.

Type of Collaborative Activity:

Research Initiative

Year the Collaborative Activity Originated:

2021

NIH Participating Institutes/Centers/Office of the Director:

NIGMS

HHS Agency Collaborators on this Activity:

FDA, ASPR, CMS